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Trajectory of the infant gut microbiome

April 5, 2013 Leave a comment

Thanks to the Night Lab at UCol. Boulder for putting this together.

“The assembly of an infant gut microbiome framed against healthy human adults “

“Here we present how a new born human gut microbial community develops from resembling the delivery method (vaginal) to look like, after almost 3 years of life, the one of an adult. This trajectory is created from the data published by Koenig JE et al. 2011 framed around the data generated by the Human Microbiome Project (HMP).”

Tasters Needed for Sensory Study!

April 3, 2013 2 comments

Greetings from the sensory team at UCD!

We are conducting an exciting and fun project on spicy chicken and spicy fried rice.  We are looking for 90 participants, either male or female, to come and taste our samples.  The chicken and rice dishes will be served on two separate days.  The spicy chicken will be evaluated on Monday, 4/22 and in the morning of Tuesday, 4/23, and the fried rice in the afternoon on Tuesday, 4/23 and  Wednesday, 4/24.

In order to qualify for this study, you should be:
- Male or female

- Between 20 and 60 years old

- Of NON-Asian descent

- And able to participate in BOTH sessions during the week of April 22

- If you are not a US citizen, you need to have lived in the US for at least for 5 years 

During the session you will be asked to taste a variety of samples of chicken and fried rice, and you will need to indicate how much you like each of them.  Some of the samples contain spices and seasonings that might make them hot and spicy.  You will also be asked questions regarding your eating habits and preferences.  All your answers will be kept confidential.

If you are interested in taking part in this study, please fill out the questionnaire here:

http://www.surveymonkey.com/s/SASS2013

Your information will be reviewed to see if you qualify.  We will contact you, and if you qualify, you will be assigned to a participation slot.  If you do not hear from us for some reason, please feel free to contact us via email at kfstudy@gmail.com or phone at 530 754-4147

Thank you so much, and we are looking forward to seeing you soon.

Professor O’Mahony, Dr. Ishii and the sensory team

Categories: Uncategorized

TODAY-Bioenergy Seminar, 179 Chemistry, UC Davis

March 12, 2013 Leave a comment

Date: Tuesday March 12, 2013

Time: 4:10 pm – 5:00 pm

Location: Room 179, Chemistry

Title: Realizing the promise of engineered metabolism for fuel and chemical production
Speaker: Prof. Ramon Gonzalez (Departments of Chemical & Biomolecular Engineering and Bioengineering, Rice University; Program Manager, DOE ARPA-E

Abstract: Biological systems are capable of performing many useful functions with potential applications in energy and chemical production, environmental remediation, pharmaceutical production, and agricultural systems. However, their full potential remains unrealized due to critical knowledge gaps in our understanding of how these systems function and in our ability to engineer and control them. Our research seeks to fill in these gaps by designing and implementing novel (metabolic) engineering strategies to optimize the performance of biological systems. In this talk, I will highlight our recent progress in these areas with special emphasis on the use of systems and synthetic biology approaches to engineer novel platforms for the efficient production of advanced
fuels and chemicals.

Host: Prof. Shota Atsumi, Dept. of Chemistry, UC Davis

UC Davis Statistical Science Symposium onThe Analysis of Complex and Massive Data

March 11, 2013 1 comment

Department of Statistics University of California, Davis

The fourth annual UC Davis Statistical Science Symposium onThe Analysis of Complex and Massive Data will take place at the University of California, Davis on Saturday, April 13, 2013, 9:00am – 5:00pm, UC Davis Campus, Mathematical Sciences Building, Colloquium Room 1147

This one-day event aims at providing an interdisciplinary forum to discuss recent developments in the rapidly evolving areas relating to “Big Data” and “Data Science”.

Invited speakers include:

More details (title, abstract, schedule) will be made available at http://www.stat.ucdavis.edu/symposium2013/.

Reception after the symposium
A reception following the symposium is scheduled to begin at 6:00pm at the John Natsoulas
Gallery at 521 1st St.
in downtown Davis.  Registration
The registration for the event is free. Nevertheless, we ask all the participants to register at http://www.stat.ucdavis.edu/symposium2013. We hope to welcome many of you to this event.

UC Davis Energy Institute Seminar- Wednesday, 30 January 2013, 4:10 – 5:00 p.m.

January 29, 2013 Leave a comment

UC Davis Energy Institute Seminar, Wednesday, 30 January 2013, 4:10 – 5:00 p.m.
Location: Energy Institute Main Offices, UC Davis West Village, 1605 Tilia St., Ste. 100, Davis CA 95616
Title: Gasification of Biomass in Fluidized Beds – Thermodynamic Modeling and Experimental Analysis of Single and Multi-bed Reactors
Speaker: Malay Karmakar, Ph. D.
, Senior Scientist, Thermal Engineering Department
CSIR-Central Mechanical Engineering Research Institute (CSIR-CMERI)
Council of Scientific & Industrial Research, Government of India, New Delhi, India.

http://energy.ucdavis.edu/files/events/Karmakar_Seminar_Abstract_Bio_Directions.pdf.

Don’t Ask “What?” Ask “Why?”

December 12, 2012 Leave a comment

The following was posted on LinkedIn by CEO Tim Brown. I think what it suggests can be well applied to our scientific efforts, especially to those of young scientists in training.

To Boost Creative Thinking, Ask This Question (link to original article)

Don’t Ask “What?” Ask “Why?”
Instead of accepting a given constraint, ask whether this is the right problem to be solving.

Every parent knows how infuriating 5-year-olds can be with their constantly questioning “Why?” But for design thinkers, asking “Why?” is an opportunity to reframe a problem, redefine the constraints, and open the field to a more innovative answer.

For example Will Work For, the design provocation I wrote about earlier this week, questions the core motivations for why we work.

There is nothing more frustrating than coming up with the right answer to the wrong question. This is true whether you’re designing a new company strategy or designing the next week of your life.

A willingness to ask “Why?” will annoy your colleagues in the short run, but in the long run it will improve your chances of spending energy on the right problems.

What will you ask “Why?” about this week?

To Boost Creative Thinking, Ask This Question (link to original article)

Categories: Uncategorized

BMCDB TGIF Nov 16th @ 5:30 in LSA 1022

November 15, 2012 Leave a comment
Gobble gobble BMCDBers!
 
Come out and take a load off this Friday at 5:30 PM in 1022 LSA for this month’s TGIF! We’ll be having the standard staple graduate student diet of assorted pizzas and beer, in addition to freshly baked baguettes with spinach dip, an organic spring salad mix and tasty sun chips, and for the wine connoisseurs  we’ll be serving an Argentinian Malbec and a Californian White Zinfandel and a Californian Chardonnay. If get lost and can’t find where the party is at, just wander around the first floor of LSA and we’ll be bumpin’ 2 CHAINZZZ!
 
Also good luck to the BMCDB Bowlaz’ tomorrow, Gordon “Ball Master/Guttermouth” Walker, John “King Pin” Riggs, Johnathan “Unbowleavable” Diehl, Matthew “Pin Hunter” Blain-Hartung, and Ralphington “Big Em McCracken” McNeilage. Watch them bowl out of control at 6 to 8 PM tomorrow, Thursday November 15 at the MU bowling alley, and if you go, don’t forget to wear your BMCDB swag!
 
Bring the Dean’s Cup home fellas!
 

(`-`) (._. ) (· – ·) ( ._.) ( ‘ -’)

   The TGIF Committee

(`-`) (._. ) (· – ·) ( ._.) ( ‘ -’)

 

Inline image 2

Categories: Uncategorized Tags: , , , ,

“Modulating conformation and dynamics to interrogate cellular ubiquitin-deubiquitinase signaling”4:00 p.m. 1005 GBSF Auditorium

November 14, 2012 Leave a comment

The Genome Center & Structural Biology Focus Group Presents:
Dr. Jacob Corn
Genentech
Early Discovery
“Modulating conformation and dynamics to interrogate
cellular ubiquitin-deubiquitinase signaling”
Ubiquitin is a highly conserved eukaryotic protein that interacts with a diverse set of
partners to act as a cellular signaling hub. Intriguingly, ubiquitin has recently been
shown to be conformationally flexible, is postulated to underlie its multifaceted
recognition. Using computational and library-based means, we interrogate core
mutations of human ubiquitin that modulate its conformational dynamics and find that
human deubiquitinases involved in tumorigenesis are sensitive to ubiquitin’s
conformational state. Using this insight, we engineer new states of ubiquitin that act as
high-affinity deubiquitinase (DUB) probes to inhibit DUB activity in human cells. We
also find that certain DUBs are exquisitely sensitive to the rate with which ubiquitin
switches between states, and show that strict maintenance of the kinetics of ubiquitin’s
motion is necessary for the survival of eukaryotic cells. These results reveal the key
role protein motion plays in a major disease-associated signaling network, and for the
first time demonstrate the importance of “invisible” conformational dynamics in vivo.

Wednesday, November 14th, 2012
4:00 p.m.
1005 GBSF Auditorium
Cookies & Coffee will be provided before the seminar
Faculty Host: Justin Siegel (jbsiegel@ucdavis.edu)
(If you wish an appointment with the invited speaker, please contact the host.)

GENOME CENTER SYMPOSIUM-Oct 31st

October 30, 2012 Leave a comment

Wednesday, October 31, Halloween 2012, 8:30 AM – 4:00 PM, GBSF Auditorium
A yearly celebration of research in the Genome Center laboratories

Focus on genomics of Human Disease and on Metagenomics
8:30 AM-Breakfast, posters and carved pumpkins set up
9:00 AM-Richard Michelmore, Welcome
9:05 AM-Weston Powell, LaSalle lab, Long non-coding RNAs and Prader-Willi Syndrome
9:35 PM-New and exciting technologies in the GC Cores, an interactive forum, Joe Fass, Ryan Kim, Mine Palazoglu, Brett Phinney. Moderator: Luca Comai
10:40 AM-Break: Coffee, cookies, costumes, poster viewing
11:00 AM-Emerging Genomic Technology and Human Health, an interactive forum
Brock Siegel*, Jonathan Eisen, David Segal. Moderator: Justin Siegel
The Great Pumpkin Carving Contest
12:00 PM-Lunch, poster viewing, vote on pumpkin carvings
1:10 PM-Janet Jansson, Keynote speaker, Earth Science Division and Department of Plant and Microbial Ecology, Berkeley “Omics exploration of the human gut microbiome”
2:10 PM-Anna Guan, Rannala lab, Pooling-based GWAS for identifying lung cancer risk
variants in the Thai population
2:40 PM-Break: Refreshments, Award for best carved pumpkin
3:00 PM-Justin Siegel, Siegel lab, Engineering therapeutic proteins for celiac disease
3:30 PM-Holly Bik, Eisen lab, Phylogeny-based taxonomy assignments from environmental
metagenome datal
4:00 PM-Luca Comai, Ending comments

Refreshments provided by Fisher Scientific and associate companies, and by Illumina
Inc.
* Brock Siegel managed operations at Applied Biosystems, Illumina and Complete Genomics. He is
currently at Life Science Angels.

Categories: Uncategorized

Foods for Health Institute-Study Participants Needed

October 19, 2012 Leave a comment

The Foods for Health Institute is conducting exciting research studies at UC Davis and is in need of study participants. Benefits of participation include monetary compensation and health information.

HDL Milkshake Study
We seek women and men, aged 18-65 years old, with low levels of HDL cholesterol (for women this is less than 50 mg/dL and for men this is less than 40 mg/dL).
Contact: Nancy Rivera (888) 217-5355 or email at: ucdavis.ffhi.clinicalstudies@gmail.com

Dairy Fat Inflammation Study
We seek men and women 18-65 years old, with BMI of 30-35 OR 2 of any of the following: high fasting blood triglycerides or glucose; low HDL-cholesterol, a large waistline, or high blood pressure.
Contact: Nancy Rivera (888) 217-5355 or email at: ucdavis.ffhi.clinicalstudies@gmail.com

Lactation Study
We seek healthy women in their third trimester of pregnancy diagnosed with or without gestational diabetes who live in Davis, Dixon, and Woodland areas. Participants will receive complimentary in-home lactation consultations from the study’s board-certified lactation consultants.
Contact: Melissa Breck (888) 217-5355 or email at: ucdmilkstudy@gmail.com

Donor Milk Study
We seek unwanted collected frozen breast milk from healthy women who gave birth to healthy term infants within the last year who live in Davis, Dixon, and Woodland areas.
Contact: Melissa Breck (888) 217-5355 or email at: ucdmilkstudy@gmail.com

For more information about all of these studies please visit our website at: http://ffhi.ucdavis.edu/gi/hs

Thank you!
FFHI Study Volunteer Recruitment Team

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