Home > Interesting link > Longevity epigenetic inheritance in C. elegans

Longevity epigenetic inheritance in C. elegans

Read the complete article via the theguardian by Ed Yong.

C. elegans

Photograph: PA

“Long-lived worms can transmit their extended lifespan to the next generation by passing on changes in the way their genes are used, rather than differences in DNA itself.

A study has shown that nematode worms can inherit a ‘memory of longevity from their parents, even though their genome remains unchanged.

It is not clear if the same processes apply to humans, but Anne Brunet from Stanford University, who led the study, noted that some genes that affect the lifespan of nematodes were later found to influence human longevity too. ‘In several cases, the worm has proved to be a good model for humans, who live 2,000 times longer,’ she said…”

Original manuscript can be found here published in Nature.

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