Archive for October, 2012

Graduate Student Mixer: 11/1/12 5-8PM @ Bistro 33

October 30, 2012 Leave a comment

Dear Students & Staff,

Please join us in welcoming incoming graduate students and welcoming back returning graduate students. This social mixer is hosted by the Community Graduate Student Researchers on the UC Davis campus.

There will be free appetizers for and discounted drinks for hungry grad students & their supporters!
Please forward this event to members of your cohort. You can RSVP on facebook at

We can’t wait to see you at Bistro. Cheers!
Signed Your Community GSRs-

Elisa Oceguera- Lesbian, Gay, Bisexual, Transgender Resource Center (LGBTRC)
Kenya Mitchell – Cross Cultural Center (CCC)
Le Phan – Student Recruitment and Retention Center (SRRC)
Maria Elena Rodriguez -Women’s Resource and Research Center (WRRC)


Categories: Social Events, UC Davis


October 30, 2012 Leave a comment

Wednesday, October 31, Halloween 2012, 8:30 AM – 4:00 PM, GBSF Auditorium
A yearly celebration of research in the Genome Center laboratories

Focus on genomics of Human Disease and on Metagenomics
8:30 AM-Breakfast, posters and carved pumpkins set up
9:00 AM-Richard Michelmore, Welcome
9:05 AM-Weston Powell, LaSalle lab, Long non-coding RNAs and Prader-Willi Syndrome
9:35 PM-New and exciting technologies in the GC Cores, an interactive forum, Joe Fass, Ryan Kim, Mine Palazoglu, Brett Phinney. Moderator: Luca Comai
10:40 AM-Break: Coffee, cookies, costumes, poster viewing
11:00 AM-Emerging Genomic Technology and Human Health, an interactive forum
Brock Siegel*, Jonathan Eisen, David Segal. Moderator: Justin Siegel
The Great Pumpkin Carving Contest
12:00 PM-Lunch, poster viewing, vote on pumpkin carvings
1:10 PM-Janet Jansson, Keynote speaker, Earth Science Division and Department of Plant and Microbial Ecology, Berkeley “Omics exploration of the human gut microbiome”
2:10 PM-Anna Guan, Rannala lab, Pooling-based GWAS for identifying lung cancer risk
variants in the Thai population
2:40 PM-Break: Refreshments, Award for best carved pumpkin
3:00 PM-Justin Siegel, Siegel lab, Engineering therapeutic proteins for celiac disease
3:30 PM-Holly Bik, Eisen lab, Phylogeny-based taxonomy assignments from environmental
metagenome datal
4:00 PM-Luca Comai, Ending comments

Refreshments provided by Fisher Scientific and associate companies, and by Illumina
* Brock Siegel managed operations at Applied Biosystems, Illumina and Complete Genomics. He is
currently at Life Science Angels.

Categories: Uncategorized

BMCDB SSS: Gordon Walker “Establishment of Prions in Wine Strains of Saccharomyces cerevisiae as a Cause of Sluggish and Arrested Fermentations”

October 29, 2012 Leave a comment


31 October 2012

1022 LSA @ 11:00

Student Seminar Series presents:

Gordon Walker

“Establishment of Prions in Wine Strains of Saccharomyces cerevisiae as a

 Cause of Sluggish and Arrested Fermentations”

Free Pizza

Come down for science and lunch

Costumes are encouraged!!

May the yeast be with you:

New “prime and pull” vaccine model offers new hope against retroviruses

October 19, 2012 Leave a comment

Excerpt from ScienceTechDaily

New Model for Vaccination Against Genital Herpes

Until now, most efforts to develop a vaccine have focused on the immune system’s antibodies, or T cells, circulating through the body. When T cells encounter foreign invaders such as bacteria or viruses, they learn to recognize them and mount ever-stronger immune responses to fight them. But efforts to harness these circulating T cells have not been effective in organs such as the vagina, intestines, lung airways, and central nervous system, which restrict the entry of these “memory” T cells.

To investigate an alternative approach, the Yale team focused instead on peripheral tissue in the female genital tract, where viral exposure occurs. The challenge was to recruit virus-specific T cells into the vaginal mucosa without triggering a potentially harmful inflammatory response of the immune system.

Working with mice, they explored a two-part vaccine strategy they call “prime and pull.” The “priming” involved conventional vaccination to elicit a system-wide T cell response. The “pulling” involved recruitment of activated T cells directly into the vaginal tissue, via topical application, of chemokines — substances that help mobilize the immune cells.


The original study can be found here

A vaccine strategy that protects against genital herpes by establishing local memory T cells by Haina Shin & Akiko Iwasaki

Most successful existing vaccines rely on neutralizing antibodies, which may not require specific anatomical localization of B cells. However, efficacious vaccines that rely on T cells for protection have been difficult to develop, as robust systemic memory T-cell responses do not necessarily correlate with host protection1. In peripheral sites, tissue-resident memory T cells provide superior protection compared to circulating memory T cells2, 3. Here we describe a simple and non-inflammatory vaccine strategy that enables the establishment of a protective memory T-cell pool within peripheral tissue. The female genital tract, which is a portal of entry for sexually transmitted infections, is an immunologically restrictive tissue that prevents entry of activated T cells in the absence of inflammation or infection4. To overcome this obstacle, we developed a vaccine strategy that we term ‘prime and pull’ to establish local tissue-resident memory T cells at a site of potential viral exposure. This approach relies on two steps: conventional parenteral vaccination to elicit systemic T-cell responses (prime), followed by recruitment of activated T cells by means of topical chemokine application to the restrictive genital tract (pull), where such T cells establish a long-term niche and mediate protective immunity. In mice, prime and pull protocol reduces the spread of infectious herpes simplex virus 2 into the sensory neurons and prevents development of clinical disease. These results reveal a promising vaccination strategy against herpes simplex virus 2, and potentially against other sexually transmitted infections such as human immunodeficiency virus.


Foods for Health Institute-Study Participants Needed

October 19, 2012 Leave a comment

The Foods for Health Institute is conducting exciting research studies at UC Davis and is in need of study participants. Benefits of participation include monetary compensation and health information.

HDL Milkshake Study
We seek women and men, aged 18-65 years old, with low levels of HDL cholesterol (for women this is less than 50 mg/dL and for men this is less than 40 mg/dL).
Contact: Nancy Rivera (888) 217-5355 or email at:

Dairy Fat Inflammation Study
We seek men and women 18-65 years old, with BMI of 30-35 OR 2 of any of the following: high fasting blood triglycerides or glucose; low HDL-cholesterol, a large waistline, or high blood pressure.
Contact: Nancy Rivera (888) 217-5355 or email at:

Lactation Study
We seek healthy women in their third trimester of pregnancy diagnosed with or without gestational diabetes who live in Davis, Dixon, and Woodland areas. Participants will receive complimentary in-home lactation consultations from the study’s board-certified lactation consultants.
Contact: Melissa Breck (888) 217-5355 or email at:

Donor Milk Study
We seek unwanted collected frozen breast milk from healthy women who gave birth to healthy term infants within the last year who live in Davis, Dixon, and Woodland areas.
Contact: Melissa Breck (888) 217-5355 or email at:

For more information about all of these studies please visit our website at:

Thank you!
FFHI Study Volunteer Recruitment Team

Save the date…Symphony of the Soil

October 14, 2012 Leave a comment

Screening of the film, Symphony of the Soil, and pre-show fundraising reception with filmmaker, Deborah Koons Garcia

When:     Saturday, Nov. 17, 2012

5:00-6:30pm Fundraiser reception, $15 in advance or $20 at the door, includes appetizers and one glass of wine, beer or non-alcoholic beverage

All proceeds will benefit a scholarship fund for students to attend UC Davis’s Soil Science course: Field Studies of Soils in California Ecosystems (SSC 205)

6:30pm Movie, followed by Q&A, Entrance is free

Where:  1001 Giedt Hall on the UC Davis campus

“Symphony of the Soil is a 104-minute documentary feature film that explores the complexity and mystery of soil. Filmed on four continents and sharing the voices of some of the world’s most esteemed soil scientists, farmers and activists, the film portrays soil as a protagonist of our planetary story. Using a captivating mix of art and science, the film shows that soil is a complex living organism, the foundation of life on earth. Yet most people are soil-blind and “treat soil like dirt.” Through the knowledge and wisdom revealed in this film, we can come to respect, even revere, this miraculous substance, and appreciate that treating the soil right can help solve some of our most pressing environmental problems.”

Tickets for fundraiser reception will be available for purchase soon on the Agricultural Sustainability Institute’s website(

Hosted by UC Davis Soils and Biogeochemistry Graduate Group

Sponsored by the Agricultural Sustainability Institute

Categories: Uncategorized

BMCDB TGIF 10/12/12 5:30 LSA 1022

October 10, 2012 Leave a comment

Hey BMCDBers!

Come out this Friday for our last outdoor TGIF of the year! There will be plenty of beer, wine and pizza, and we’ll be having salad as a healthy option! And as if you hadn’t had enough of it, we’ll be playing all your favorite 2012 summer songs including Call me Maybe and all the Gangnam you want until your ears bleed! As the Starks say, Winter is coming, so come and enjoy the last bit of sunshine of the year!

5:30 PM in the LSA 1022 (moved due to inclement weather)

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The itty bitty TGIF Comittee

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